Infected 5 people in South Africa. 4 of them died and 1 is still in serious condition. This comes from ProMED:
All patients presented initially with a non-specific flu-like illness with symptoms of fever,headache and myalgia. The illness increased in severity over 7 days with all 4 patients developing diarrhoea and pharyngitis during the course of illness. A morbiliform rash on the face and trunk was reported in 4 cases on day 6 – 8 of illness. Facial swelling occurred in 3 patients. There appeared to be an initial clinical improvement after hospital admission in 3 patients, followed by clinical deterioration. Sudden and rapid deterioration with respiratory distress, neurological signs and circulatory collapse were terminal features in all patients who died. Bleeding was not a prominent feature. However, one patient had a petechial rash and another had oozing of blood from venepuncture sites. Chest pain was reported in case 1.
At the time of admission all patients had thrombocytopenia (range: 42-104 X109/L). Liver transaminases (AST and ALT) were available for 4 of 5 cases and were variable at the time of admission, however all 4 patients had raised AST and ALT during the course of their illness. Leucopenia was present on admission in 2 patients and 3 patients had a normal white blood cell count on admission. 4 patients subsequently developed leucocytosis during the course of hospitalisation. All contacts (family members, friends and healthcare staff) are being monitored with twice daily temperature measurements for a period of 21 days after the last exposure to a known case. In addition, safe burial of the deceased has been supervised by environmental health officers. Full personal protective equipment (PPE) and isolation precautions as per VHF protocols have been instituted.
The causative agent in this outbreak was initially identified as an Old World arenavirus by immunohistochemical tests performed at the Infectious Diseases Pathology Branch of the Centers for Disease Control and Prevention in Atlanta, USA, and on autopsy liver and skin samples taken with biopsy needles and skin punches in the Special Pathogens Unit of the National Institute for Communicable Diseases, National Health Laboratory Service, Sandringham (SPU-NICD/ NHLS), South Africa, from cases 2 and 3 on 9 Oct 2008 under biosafety level 4 laboratory conditions. Subsequently, infection with an Old World arenavirus has been confirmed in all 5 cases by positive PCR results and virus isolation by SPUNICD/ NHLS and CDC. Analysis of sequencing data generated at SPU-NICD/NHLS, Columbia University, New York, and CDC, Atlanta appears to indicate that the current outbreak is caused by a unique Old World arenavirus.