Monotherapy with oseltamivir shows greater efficacy than its combination with zanamivir, and than zanamivir alone, in patients with seasonal influenza, according to a study presented here at the 20th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID).

“Theoretically, the combination of 2 antivirals would be more powerful and diminish the risk of developing resistant strains,” said Cécile Charlois-Ou, MD, Department of Infectious Diseases, University of Paris, Paris, France, during a presentation on April 13. [snip]

[Presentation title: Efficacy of Combined Oseltamivir-Zanamivir Compared to Monotherapy of Each in Treatment of Seasonal Influenza: A Randomized, Double-Blind, Placebo-Controlled Trial. Abstract O501]

Link to program:

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