Swine flu vaccine makers may rely on a U.S. emergency declaration to use experimental additives made by GlaxoSmithKline Plc and Novartis AG to boost a limited supply of shots that will be available to fight the pandemic.

The ingredients, known as adjuvants, may be added for the first time to flu shots in the U.S. Health officials, meeting today at the U.S. Centers for Disease Control and Prevention in Atlanta, plan to discuss use of the additives, and may also recommend who should be first to receive the limited amount of vaccines drugmakers say they will begin delivering in October.

The U.S. Health and Human Services Department declared a public health emergency over swine flu in April, and the Food and Drug Administration has the power to allow the use of unapproved medical products during such a crisis. The U.S. has been slow to approve the use of adjuvants because of safety concerns, and for fear of giving Americans an excuse to avoid getting the shots, said John Treanor, a University of Rochester researcher.

“The question is, do you really feel comfortable throwing this new thing into the mix and do you really need to?” said Treanor, a professor of medicine, microbiology and immunology at the school in Rochester, New York. “I myself, if I had to do it, would really wrestle with that decision.”

The CDC agreed to pay London-based Glaxo and Novartis, based in Basel, Switzerland, more than $415 million for adjuvants that could be added to the swine flu vaccines, according to a July 13 statement.

continued

http://www.bloomberg.com/apps/news?pid=20601103&sid=a_xObcaSxF2o

 

Genetic Changes in Pandemic H1N1 in Brazil Raise Concerns
Recombinomics Commentary 19:40
July 29, 2009

“The family Laguna had eight other cases of swine flu confirmed: mother, father, younger brother, three cousins, grandmother and an aunt of the girl. .
 
The above translation describes pandemic H1N1 infections in family members of the first confirmed H1N1 fatality in the Sao Paulo metropolitan region.  The 11 year old girl, from Osasco (see map) died on June 30 and H1N1 was isolated from her blood on July 3.  The HA sequence of the isolate, A/Sao Paulo/43812/2009, was released at Genbank and has three newly acquired polymorphisms.  One polymorphism encodes for V252M (H3 numbering) and the nucleotide change is found in a limited number of sequences, including those from the 1918 pandemic.  Other human H1N1 sequences include 2006 isolates from Peru and H1N1 isolates in circulation prior to the 1957 H2N2 pandemic.  These human isolates have V252I.  However, V252M is found in the 2001 swine isolate from Hong Kong, A/swine/Hong Kong/NS1659/2001 (see list here).

continued

http://www.recombinomics.com/News/07290901/H1N1_V252M.html

 

Indonesia: Students Show Signs of Bird Flu

July 29, 2009

Malang:  The Caretaker of the Islamic boarding school of Babussalam Desa Banjar Rejo, Kecamatan Pagelaran, of Kabupaten Malang, East Java said that most of his students who were sick with signs of bird flu were treated in their respective houses. That was sent by the Caretaker of Boarding School Babussalam, Busthorik, to ELSHINTA, on Wednesday (29/7).

The boarding school personnel informed some parents of the students, especially the students whose conditions did not improve in two days.  By being sent home, the students were expected to be able to receive more intensive maintenance.  In the boarding school they personally still had dozens of students who were treated in the sick bay or in the students’ rooms.  They were separated from healthy students to avoid the spread of the illness.  From the available data in the boarding school, around 190 students experienced signs of the high fever, coughing and sore throat. The illness of these students, according to Busthorik, happened almost simultaneously at the time that a number of the residents’ chickens around the boarding school died suddenly.  

toggletext translated

orginal article

http://www.elshinta.com/v2003a/readnews.htm?id=76114

 

Mexico: 16 thousand 19 cases of influenza AH1N1

The Secretariat of Health informed that from the 21 to the 28 of July they increased of 14 thousand 861 cases of Influenza A (19 H1N1) confirmed to 16 thousands, lapse in which the deaths from 138 to 142 were increased.

In his weekly report, it detailed that of the 142 deaths, 50,7 percent were women and 49,3 percent men, of which, the 70,4 percent had between 20 and 54 years of age.

Also, it indicated that in all the organizations cases of contagion are registered, being Chiapas to the one that concentrates the greater number of patients, followed by Yucatan, Federal District, Jalisco, Tabasco, Veracruz and Guerrero.

google translated

orginal article

http://www.exonline.com.mx/XStatic/excelsior/template/content.aspx?se=primera&su=pulsonacional&id=675029&te=nota

 Argentina: 322 deaths confirmed More Death Than US

The report notes that in the midst of a possible new influenza A peak in August, Argentina is the country with more deaths due to influenza in the world. These data come from reports provided by provincial Ministries of Health.

With a total of 322 deaths until today (yesterday), Argentina surpassed the 2 countries that accounted for the greatest number of deaths: Mexico and the USA. The first reports on 138 deaths, although the WHO recorded the last part, 119. U.S. is on the 263 fatalities, while the WHO reports 170. ….

google translated

http://www.ultimahora.com/notas/241780-Argentina-ser%C3%ADa-el-pa%C3%ADs-con-m%C3%A1s-cantidad-de-muertos-por-A-H1N1In

 

Australia
•  New South Wales: Sudden jump in state’s swine flu death toll (Link)
•  Swine Flu Related Death (Link)

Bulgaria
•  Two children test positive for swine flu in Varna (Link)

Canada
•  Alberta: Family survives ordeal (Link)

Central Asia
•  Afghanistan and Kazakhstan – First influenza cases detected (Link)

India
•  5 more quarantined  (Link)
•  Seven more test positive for H1N1 flu in Pune (Link)

Ireland
•  Swine flu surge as 500 ‘infected’ in one week (Link)

Malaysia
•  Fourth flu death (Link)
•  More Varsities And Schools Closed (Link)

Mexico
•  16 thousand 19 cases of influenza AH1N1 (Link)

New Zealand
•  H1N1 09 Swine Flu update on cases (Link)
•  Swine flu cases still rising  (Link)

Saudi Arabia
•  Investigation into swine flu death  (Link)

Taiwan
•  Taiwan diagnoses 6 Hong Kong medical students with H1N1 (Link)

Thailand
•  All flu patients must seek attention within two days – and new death (Link)
•  21 more Thai fatalities (Link)

United Kingdom
•  Tamiflu ‘sold at car boot fairs’ (Link)
•  Swine flue h its 14 at tax centre (Link)
•  Universities prepare for swine flu worst as nurseries take away soft toys (Link)

United States
•  VA: 2 Albemarle Co. Employees Have Swine Flu  (Link)
•  CA: Orange Cty Fair employee diagnosed with swine flu  (Link)
•  CA: Orange Cty men’s jail closed because of swine flu  (Link)
•  NV: 3 H1N1 Cases Confirmed at Sierra Nevada Job Corps  (Link)
•  VA: State records another swine flu-related death  (Link)
•  VA: Saltville police officer likely hit with swine flu  (Link)
•  MO: Swine flu strikes Lesterville summer camp  (Link)
•  CA?: Illness, deployments hit one middle school hard  (Link)
•  Montana cases 122  (Link)
•  Swine Flu Shot in U.S. May Rely on Emergency Use of Additives (Link)
•  DC: Four Senate pages display swine flu symptoms (Link)
•  A New Airport Ritual, Swine Flu Screening (Link)
•  GA: Global trade system raises flu virus’s threat (Link)
•  FL: diabetic mom’s swine flu death shocks Palm Beach County family (Link)
•  DC: Six Senate Pages Come Down With ‘Flu-Like Symptoms’ (Link)
•  Swine flu deaths fuel anxiety (Link)
•  Oregon to hold swine flu summit in Salem (Link)
•  Colorado has first confirmed swine flu death  (Link)
•  US Military Poised to Help FEMA Battle Swine Flu Outbreak (Link)
•  U.S. unprepared for second wave of swine flu, report finds  (Link)
•  OR: Young Life outbreak confirmed as H1N1  (Link)
•  FL: 11 Confirmed Cases of Swine Flu in Bay  (Link)

Vietnam
•  Vietnam’s highland province reports first H1N1 case (Link)
•  H1N1 virus closes another city school, Viettel office infected (Link)

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