By Helen Branswell (CP) – 14 hours ago

 

TORONTO — A flurry of innovative vaccine trials is in the offing as governments and regulatory agencies prepare for the probable launch of mass swine flu vaccination programs in the fall.

The results of the trials could determine whether people with egg allergies can be offered pandemic (and regular) flu vaccine, whether pandemic and seasonal flu shots could be given at the same time and whether one company’s vaccine can be given with another’s adjuvant, a compound that boosts its potency.

Vaccine manufacturers are either unable or unlikely to undertake the complicated studies required to answer these questions. Governments will fund the work instead.

Infectious diseases expert Dr. Anthony Fauci says the goal here for organizations like the U.S. National Institute of Allergy and Infectious Diseases – which he heads – is to fill key knowledge gaps for vaccine regulators.

“What are they going to need that somebody else can’t do?” Fauci explains.

Some of those priorities will be aired Thursday in Washington when the U.S. Food and Drug Administration’s vaccine and related biological products advisory committee meets in a session on clinical trials for pandemic vaccines.

Vaccine manufacturers will do the basic testing, work designed to assure regulators and would-be recipients that their vaccine is safe and likely to protect against the pandemic strain, an H1N1 virus of swine origin.

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Africa
•  Swine flu Spreading too Fast (Link)

Argentina
•  School Closure Will not Extend Past August 3: Argentina (Buenos Aires) (Link)
•  Mendoza, Argentina: Government Says The Worst Is Over, However there are Doubts about Numbers of Patients (Link)
•  Request to Postpone Payment of Taxes Due to Flu A (Link)

Australia
•  Third man with swine flu dies in Northern Territory (Link)
•  Workforce hit as doctors predict swine flu peak (Link)

Belgium
•  Belgians choose health over good manners  (Link)

Brazil
•  Brazilian army to patrol southern border to contain A/H1N1 flu (Link)

Brunei
•  ‘Visitors Shouldn’t Be Alarmed By Statistics’ (Link)

Canada
•  Toronto: Mayor urged to ‘correct’ H1N1 plan  (Link)
•  Ontario: Another summer camp reports swine flu (Link)
•  Officials focus on H1N1 plan ahead of Olympics (Link)

Chile
•  Swine flu infections falling in Chile (Link)

China
•  Medford, Oregon student tests positive for swine flu in China (Link)
•  More UK pupils hospitalised in China: quarantine with no Tamiflu? (Link)
•  Fifth British child on China trip has suspected swine flu (Link)
•  Macao’s A/H1N1 confirmed cases climb to 107  (Link)
•  Chinese mainland A/H1N1 flu cases top 1,500  (Link)
•  Hong Kong reports 108 new cases of Influenza A/H1N1 (Link)

Egypt
•  Three new cases of swine flu and the number up to 120 cases  (Link)
•  28-year-old country’s first swine flu death (Link)

Guyana
•  Conjuntivitis associated with swine flu (Link)

India
•  Two cases of swine flu in Chandigarh (Link)
•  Staff warned against speaking with media  (Link)
•  Delhi and Pune show largest local flu spread  (Link)

Indonesia
•  Jakarta: 4,000 Islamic School Pupils Quarantined (Link)
•  No vaccine yet (Link)

Iran
•  Two swine flu patients cured in Iran (Link)

Japan
•  Japan flu cases top 4,000 (Link)

New Zealand
•  Sick teachers, students told to stay home, as holidays end (Link)

Saudi Arabia
•  Saudi swine flu cases near 300 (Link)
•  Swine flu spreading (Link)

Singapore
•  First H1N1-related death in Singapore (Link)

South Korea
•  Flu infections nearing 1,000 (Link)

Thailand
•  Thailand: Masks for Forum delegates (Link)
•  Bangkok: New guidelines for H1N1 victims (Link)

United Kingdom
•  Pregnancy flu advice highlighted (Link)
•  Swine flu in Britain: The guessing game  (Link)
•  Clues from 1918 graves which may save us all  (Link)
•  LONDON: Swine flu advice re-issued for pregnant women (Link)
•  Scotland: Planning for worst-case flu scenario (Link)
•  Swine flu threat greater than terrorism (Link)
•  Confusion and contradictions as health chiefs go off message (Link)

United States
•  Florida – Baby of woman with swine flu dies; mother critical (Link)
•  Oregon – Swine flu hitting local residents  (Link)
•  Swine Flu Vaccine Fast-Tracked to September?  (Link)
•  Summer camps: Swine flu isn’t taking a vacation  (Link)
•  Indiana reports Lake County H1N1 flu death (Link)
•  Maryland – Summer camps deal with swine flu
(Link)
•  CT: Experts: Swine Flu Is Waning, Will Return In The Fall (Link)
•  California – Placer County woman dies of swine flu infection  (Link)
•  Wisconsin – WIS: Fifth person in state has died (Link)
•  North Carolina – 2 suspected cases of swine flu found in Haywood (Link)
•  San Diego, CA: Swine Flu Spreads to County Jail (Link)
•  Arizona: Law creates new vaccine data system (Link)
•  Minnesota Health Department officials fear flu mutation (Link)
•  Wisconsin: Chippewa County girl’s swine flu case raises awareness (Link)
•  Florida: Swine flu at Bible School (Link)
•  43 cases of H1N1 in South Dakota (Link)
•  California – Marin sees increase in flu cases
(Link)
•  Florida – Swine flu is back with a vengeance (Link)
•  New Jersey: 10th Gloucester County swine flu case confirmed (Link)
•  North Carolina: Central Univ campers diagnosed with H1N1 virus (Link)

Vietnam
•  Vietnam increases hospital support amid H1N1 patient overload (Link)
•  Seven more H1N1 cases detected in Vietnam  (Link)

Commentary
•  Swine flu is spreading even in summer  (Link)
•  China has a case of swine flu phobia  (Link)
•  This time we dodged a bullet (Link)
•  Swine flu adds a new dimension to a father’s fear (Link)

General
•  Over 160 new A/H1N1 flu cases confirmed in Europe (Link)
•  BA and Virgin to stop suspected swine flu victims from flying (Link)

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