Of the 36 flu viruses subtyped at the state lab during week 51, 28 (78%) were seasonal A/H3N2, 3 (8%) were unsutypeable (sic), 3 (8%) flu type B and 2 (6%) the 2009 A/H1N1.

The above comments from the week 51 report from Pennsylvania cite three unsubtypable samples, which is unusual in 2010. Last year there were samples that were influenza A positive but unsubtypable because they were swine H1N1, and subtyping was done with reagents directed against human H1 and human H3. The swine cases were subsequently identified with reagents that targeted the swine H1.

Pennsylvania has reported trH3N2 previously, but the trH3N2′s have a human H3 from the mid-1990′s. It is possible that the human H3 sub-typing reagents would fail to recognize trH3N2, because it continues to evolve away from seasonal H3. If there really are three new trH3N2 cases in PA, it would be the highest number of novel influenza in a given state since pandemic H1N1 was identified in California
if these are three new trH3N2 cases, the sequences should be released and an alert should be made.


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South Korea
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•  Man dies of H1N1 in metro hospital (Link)
•  After foot-and-mouth, avian flu feared spreading (Link)

•  S Korea confirms outbreak of H5N1 in two provinces (Link)

Sri Lanka
•  Sri Lanka swine flu outbreak kills 22 (Link)

United Kingdom
•  Swine flu kills Queen’s patient (Link)
•  Swine flu alert at hospital (Link)
•  GPs report flu cases rose again last week  (Link)
•  Cases of flu increase more than 40% (Link)
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•  Arrowe Park hospital suspends in-patient visiting to reduce spread of flu (Link)

•  Winter flu claims two more lives in Scotland  (Link)
•  Cornwall Hospital puts doctors on alert over flu (Link)
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United States
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•  CDC: Flu season picks up, widespread in 5 states (Link)

•  Flu Activity on the Rise (Link)

•  CIDRAP: Flu activity up globally, in US, and notably in UK (Link)

•  Adjuvanted pandemic flu vaccine efficacious in children and young adults (Link)

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•  Recombinomics: UK H1N1 ICU Cases Spike To 738 (Link)


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